When one contemplates the universe of U.S. agencies researching, investigating, and gathering intelligence on potential terror targets and methods, the Environmental Protection Agency (EPA) rarely makes the list. Since the mid-1990s, however, and increasingly following the terror attacks of 9/11, EPA researchers, scientists, intelligence analysts, engineers, computer forensic specialists, and special agents have played key roles in understanding, preparing for, preventing, and responding to threats and attacks utilizing chemicals and biotoxins, targeting the United States’ water infrastructure, or being aimed at the chemical manufacturing sector.