Many roads lead to highway safety because there is no single route that will prevent all fatalities, serious injuries, and crashes regardless of cause. The four Es—education, emergency medical services, enforcement, and engineering—travel multiple roads at various times and for different purposes in order to reduce highway carnage. This Highway Safety–themed issue of Police Chief magazine moves along five different roadways connected by speed reduction, impaired-driving countermeasures, and seat belt enforcement toward achieving highway safety.